Amniotic Band Sequence: A Case Report

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Aniruddh Agrawal
Adit Singhal
Sohum Shah
Arun Chutani
Anisha Agrawal
Siddhant Bhargava


Background: Amniotic band sequence (ABS) is a rare condition in which parts of a fetus get entangled by the amniotic bands attached to the fetal surfaces and structures. This can lead to grotesque structural fetal anomalies or constriction rings that appear in-utero. The severity of this condition ranges from visceral herniation or mild constriction to complete amputation of a digit or limb. This anomaly affects one infant out of 11,200 and this number has shown a stable trend during the last 17 years. Management of this condition is individualized and can include Z-plasty, W-plasty and other such cosmetic surgeries for mild conditions. Severe conditions may require neurovascular reconstruction and even amputations.

The Case: This paper reports a 6-month-old female who presented with constriction rings on both lower limbs and on the upper left limb. She was the youngest of 3 siblings, none of which presented with amniotic band sequence at birth. The child was of an African descent and was born in Tanzania to parents of a standard economic class. The condition was observed at birth and not in-utero. The baby was brought to a tertiary care hospital in Mumbai, India where she underwent Z-plasty surgery. The baby has now recovered from the surgery and appears to be in good shape.

Conclusion: The etiology of the amniotic band sequence is still not clear. The mother of the patient provided a history free from illnesses or abnormal discomfort during the term of the pregnancy. Identification of this anomaly in the pre-natal periods is very important as one can initiate preventive measures. Prenatal ultrasonography is the only screening method to diagnose these deformities.

Amniotic band syndrome, amniotic band sequence (ABS), constriction deformities, syndactyly

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How to Cite
Agrawal, A., Singhal, A., Shah, S., Chutani, A., Agrawal, A., & Bhargava, S. (2016). Amniotic Band Sequence: A Case Report. International Journal of Medical and Pharmaceutical Case Reports, 7(5), 1-5.
Case Study