International Journal of Medical and Pharmaceutical Case Reports http://www.journalijmpcr.com/index.php/IJMPCR <p style="text-align: justify;"><strong>International Journal of Medical and Pharmaceutical Case Reports (IJMPCR) (ISSN: 2394-109X)</strong> aims to publish case reports in the areas of medical and pharmaceutical sciences.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.&nbsp;</p> en-US contact@journalijmpcr.com (International Journal of Advances in Nephrology Research) contact@journalijmpcr.com (International Journal of Advances in Nephrology Research) Mon, 09 Sep 2019 09:03:05 +0000 OJS 3.1.1.4 http://blogs.law.harvard.edu/tech/rss 60 Detection of Metastatic Breast Carcinoma Cells in Bone Marrow by Flow Cytometry http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30105 <p>Breast cancer is the most common cause of cancer death in women worldwide. Cytological, histological, and immunohistochemical techniques are routine laboratory tests for determining tumor subtypes. Over the past few years, laboratory diagnostic tests for breast cancer have become more complex, sophisticated, and specialized. This report describes the case of a young patient with metastatic breast cancer whose diagnosis was based on flow cytometric analysis of bone marrow aspirate. Flow cytometry showed to be an important tool in cancer diagnosis. Its application as a routine laboratory test for the diagnosis of solid tumors, such as breast cancer, can help provide fast results while increasing diagnostic coverage.</p> Manoela Lira Reis, Daniella Serafin Couto Vieira, Laura Otto Walter, Maria Claudia Santos-Silva ##submission.copyrightStatement## http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30105 Mon, 09 Sep 2019 00:00:00 +0000 Vocal Folds: An Unusual Hideout for Systemic Sarcoidosis http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30106 <p>Sarcoidosis is a chronic inflammatory granulomatous disease of unknown etiology. It can expand to all organs and tissues. Lungs and lymph nodes are the most commonly involved tissues. Laryngeal sarcoidosis is rare, accounting for no more than 1% of patients with systemic sarcoidosis. We herein report the case of a 51-year-old female presenting a two-year history of persistent voice hoarseness with direct laryngoscopy findings of epiglottis swelling and irregular swelled and bruised left vocal fold. Histological examination highlighted the presence of non-caseating granulomas. Further investigations revealed similar histological findings in the nasal cavity as well as lymphocytic alveolitis. It also showed the presence of phalangeal bone lesions of both hands. All these pointed to the diagnosis of sarcoidosis with upper respiratory tract (nasal and laryngeal), lung and bone involvement. The patient was started on 0.5 mg/kg daily of prednisone for 1 month followed by progressive tapering with lasting favorable outcome.</p> Anis Hariz, Abir Derbel, Ines Kechaou, Imène Boukhris, Mohamed Salah Hamdi, Eya Cherif ##submission.copyrightStatement## http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30106 Mon, 04 Nov 2019 00:00:00 +0000 Sunitinib Use for Metastatic Renal Cell Carcinoma Associated with Necrotizing Cavitary Pulmonary Aspergillosis with Aspergillus flavus: Case Report and Review of Literature http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30107 <p>Sunitinib associated chronic necrotizing cavitary pulmonary aspergillosis has rarely been reported in literature. This article describes a patient with biopsy proven papillary renal cell carcinoma initially treated by radical nephrectomy. He presented about 8 months later with progressively worsening abdominal pain, headache, weight loss of 40 pounds and investigation revealed extensive retroperitoneal and mediastinal lymphadenopathy with brain metastasis. He was evaluated by oncology and started on cycles of sunitinib with dexamethasone, which he took for about 6+ months. He presented to the hospital in respiratory distress requiring intubation and ICU admission and CT scan of thorax revealed a new large consolidation with necrosis and a cavity. Given suspicion of opportunistic fungal infection with sunitinib, he was started on empiric Vancomycin, Zosyn and Voriconazole. He underwent bronchoscopy, bronchoalveolar lavage and cultures revealed <em>Aspergillus flavus. </em>Subsequently serum and BAL (Bronchoalveolar Lavage) galactomannan were reported positive as well. Given poor prognosis, patient’s family elected for comfort measures.</p> Suganthini Krishnan Natesan ##submission.copyrightStatement## http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30107 Mon, 18 Nov 2019 00:00:00 +0000 Iatrogenic Right Hepatic Duct, Right Posterior Hepatic Duct, Right Hepatic Artery and Duodenum Injury during Routine Laparoscopic Cholecystectomy Due to Symptomatic Gallstones: Rare but Serious Complication - Case Report and Literature Review http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30108 <p>Laparoscopic cholecystectomy is a very frequent surgical procedure with a low complication rate. The reasons for such complications range from anatomical anomalies, obesity, poor exposure of anatomic structures, bleeding or lack of surgical experience. If complications arise, prompt recognition and correct management are essential. Early and correct treatment allows avoidance of serious complications, such as secondary biliary cirrhosis, hepatic failure, and ultimately death. In this paper is presented a case of a 40-years-old male patient, who sustained iatrogenic major bile duct, right hepatic artery and duodenum injury during routine laparoscopic cholecystectomy due to symptomatic gallstones.</p> Jurij Janež ##submission.copyrightStatement## http://www.journalijmpcr.com/index.php/IJMPCR/article/view/30108 Wed, 20 Nov 2019 00:00:00 +0000