Stevens-Johnson Syndrome Treated with Ozone Hemo Therapy: A Case Report
Lamberto Re *
Clinical Pharmacology - Ozone Therapy Department, Medinat SAS, Via Fazioli 22, 60021 Camerano, Ancona, Italy.
Giuseppe Malcangi
Clinical Pharmacology - Ozone Therapy Department, Medinat SAS, Via Fazioli 22, 60021 Camerano, Ancona, Italy.
Oriano Mercante
INRCA-IRCCS, National Institute of Health and Science on Aging, Via della Montagnola, 81, Ancona, Italy.
Cristina Gagliardi
INRCA-IRCCS, National Institute of Health and Science on Aging, Via della Montagnola, 81, Ancona, Italy.
Nadia Rampoldi
Clinical Pharmacology - Ozone Therapy Department, Medinat SAS, Via Fazioli 22, 60021 Camerano, Ancona, Italy.
*Author to whom correspondence should be addressed.
Abstract
We report a case of Stevens-Johnson Syndrome treated with ozone autohemotherapy. The patient had been diagnosed with Stevens-Johnson syndrome 3 months before admission to our clinic by the treating physician. There was ulceration of the buccal, nose and ocular mucosa (varying grade). Previous treatment with antiviral and anti-inflammatory drugs was done without any apparent result. The patient received a total of eight major autohemotherapies, with treatments administered every third day. We start with a first infusion of blood treated with low ozone doses followed by vitamin C 7.5 g. After the first treatment the patient showed a sudden relief of symptoms and the ulcers disappeared. The treatment was repeated to reach a stable condition and a follow up of six months showed the complete healing of the patient.
Keywords: Ozone, stevens-johnson syndrome, humans, ascorbic acid.