Gorlin Goltz Syndrome – A Case Report from Bosnia and Herzegovina
Asja Prohic *
Department of Dermatovenerology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Senad Muhasilovic
Private Dental Practice Dr. Muhasilovic, Sarajevo, Bosnia and Herzegovina.
Amela Kuskunovic
Department of Radiology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Besima Hadzihasanovic
Department of Radiology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Suada Kuskunovic-Vlahovljak
Institute of Pathology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Mersiha Krupalija-Fazlic
Department of Dermatovenerology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Anes Joguncic
Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
*Author to whom correspondence should be addressed.
Abstract
Gorlin-Goltz syndrome (GGS) is an uncommon inherited disorder characterized by numerous basal cell carcinomas, odontogenic keratocysts and musculoskeletal malformations. A spectrum of other neurological, ophthalmic, endocrine and genital manifestations is known to be variably associated with this triad. Diagnosis of the syndrome is based on major and minor criteria. It is important to make an early diagnosis and a proper management of GGS to reduce the severity of complications including cutaneous and cerebral malignancy.
We present a case of GGS in a 39-year-old male who met three major and several minor criteria.
Keywords: Gorlin Goltz syndrome, nevoid basal cell carcinoma syndrome, basal cell carcinomas, palmar pits, odontogenic keratocysts, calcifications of the falx cerebri.