Insulinoma and Isolated Polycystic Liver Disease: Case Report
Cristina Martínez-Berdeja
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Paloma Almeda-Valdes *
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Teresa Cuatecontzi-Xochitiotzi
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Bernardette Rivas-Gómez
Department of Internal Medicine, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Laura M. Bernal-López
Department of Pathology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Ivette Cruz-Bautista
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Carlos A. Aguilar-Salinas
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
Francisco J. Gómez-Pérez
Department of Endocrinology and Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico.
*Author to whom correspondence should be addressed.
Abstract
Gastroenteropancreatic neuroendocrine tumors are fairly rare neoplasms and their diagnosis can result defying. Polycystic liver disease is also a rare condition characterized by the formation of liver cysts. We report a case of a 59-year-old female with isolated polycystic liver disease and hypoglycemia. The prolonged diagnostic fast indicated the presence of endogenous hyperinsulinism and after distal pancreatectomy the final histological result confirmed the presence of an insulinoma. The coexistence of these two unusual clinical conditions was unexpected and there are few reported cases associating both conditions.
Keywords: Hypoglycemia, polycystic liver disease, insulinoma