Successful Treatment with Dapsone for Refractory Immune Thrombocytopenia
Yasuhiro Maeda *
Department of Hematology, National Hospital Organization, Osaka Minami Medical Center, Japan.
Kenta Yamamoto
Department of Hematology, National Hospital Organization, Osaka Minami Medical Center, Japan.
Ayano Fukui
Department of Hematology, National Hospital Organization, Osaka Minami Medical Center, Japan.
Go Eguchi
Department of Hematology, National Hospital Organization, Osaka Minami Medical Center, Japan.
Terufumi Yamaguchi
Department of Hematology, National Hospital Organization, Osaka Minami Medical Center, Japan.
*Author to whom correspondence should be addressed.
Abstract
In adult with immune thrombocytopenia (ITP), it has been known that steroids have been used as a first-line therapy. The therapy induced remission in more than 60% of patients. Here, we evaluated the results of dapsone for a steroid-resistant ITP patient. Further, dapsone has been reported to emerge as a safe and inexpensive therapy for chronic ITP. In this case, we showed a relationship between platelet count and grade of hemolysis by treatment with dapsone.
Keywords: ITP, drug-resistance, dapsone, hemolysis