A Case Report on Mucormycosis in Non-Diabetic, Non-Covid Recovered Patient with no History of Steroid use
Gautam Panduranga
Department of Internal Medicine, Krishna Institute of Medical Sciences, Hyderabad, India.
Bavu Akhil Kumar
Pharm-D,Bharat Institute of Technology,JNTU, Hyderabad, India.
Mandhala Sai Krishna
Pharm-D,Bharat Institute of Technology,JNTU, Hyderabad, India.
Akhil Aakunuri *
Department of Pharmacy Practice, Pharm-D,Bharat Institute of Technology, JNTU, Hyderabad, India.
Nikitha Godishala
Department of Pharmacy Practice, Pharm-D,Bharat Institute of Technology, JNTU, Hyderabad, India.
*Author to whom correspondence should be addressed.
Abstract
Rhino cerebral orbital mucormycosis is an aggressively spreading fungal infection caused by filamentous fungi of the Mucoraceae family and is found to be more prone in patients with comorbidities that include: uncontrolled diabetes mellitus, immune-suppressed patients, iron and aluminum overload, chronic steroid therapy, severe trauma, and protein-energy malnutrition.
A 51year old male patient was admitted to the hospital with a complaint of headache and intermittent fever. The patient had no history of diabetes or denovo hypertension. Based on the analysis of histopathological and radiological investigations, the patient was diagnosed with mucormycosis. The patient furthermore underwent an endoscopic surgical debridement followed by standard treatment including antifungal antibiotic(amphotericin-B) and azole antifungals (posaconazole) along with symptomatic treatment. Though the patient was given all possible therapy available, no improvement was seen in the patient's condition (poor prognosis).
Keywords: Mucormycosis, rhinocerebral, zygomycosis