Polycythemia Rubra Vera: A Case Report
. Ambika *
Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh-244001, India.
Ujjawal Rawat
Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh-244001, India.
Piyush Mittal
Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh-244001, India.
Ajay Kumar
Department of Clinical Medicine, Teerthanker Mahaveer Medical College and Research Centre, Uttar Pradesh, India.
*Author to whom correspondence should be addressed.
Abstract
Polycythemia vera, also denoted as polycythemia rubra vera is a Philadelphia chromosome (Ph)-negative myeloproliferative neoplasm which usually affects 2.5-10 people per 100000 people. Max cases are present in people age 60 years of age, out of which 10% patients are under the age of 40. The below presented case is an original case of 37-year-old female who presented to us with this condition with a history of insomnia, Fronto- parietal headache, a systemic itch that deteriorates after a hot water bath along with loss of concentration from last 6 weeks and early satiety, discomfort in the upper right abdomen and drastic weight loss from previous one month. The blood test depicted markedly increased hemoglobin (23.8g/dl). A bone marrow biopsy was done and it was confirmed that the patient is suffering from PRV. The patient was treated with phlebotomy, aspirin, and Ruxolitinib.
Keywords: Polycythemia vera, ruxolitinib, haemopoietic disorder, philadelphia chromosome