Horner Syndrome : Gateway to Neuro-Behçet Syndrome

Chaïmaâ Zeroual *

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

Mina Moudatir

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

Khadija Echchilali

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

Leïla Barakat

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

Safaâ Mourabit

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

Hassan El Kabli

Department of Internal Medicine, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Background: Horner syndrome (HS), a rare neurological condition caused by disruption of the oculosympathetic pathway, can occasionally serve as an early indicator of systemic diseases such as Behçet syndrome (BS). Neuro-Behçet syndrome (NBS) represents a severe manifestation of BS affecting the central nervous system (CNS). It is associated with significant morbidity.

Case Description: This report describes an unusual case of NBS revealed by HS in 43-year-old male who initially presented with progressive-onset left ptosis. The symptomatology was enriched by left-sided hemicranial headaches and homolateral carotidynia. NBS diagnosis was established after ruling out other potential differential diagnosis. The association of corticosteroids (CSs) and other immunosuppressants (ISs) led to a significant improvement.

Conclusion: Considering atypical revelation’s mode of NBS remains a noteworthy occurrence for clinicians. Prompt diagnosis and intervention are crucial to prevent further neurological deterioration.

Keywords: Behçet syndrome, neuro-behçet syndrome, horner syndrome, central nervous system, corticosteroids, immunosuppressants, case report


How to Cite

Zeroual, Chaïmaâ, Mina Moudatir, Khadija Echchilali, Leïla Barakat, Safaâ Mourabit, and Hassan El Kabli. 2025. “Horner Syndrome : Gateway to Neuro-Behçet Syndrome”. International Journal of Medical and Pharmaceutical Case Reports 18 (2):14-19. https://doi.org/10.9734/ijmpcr/2025/v18i2416.

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