International Journal of Medical and Pharmaceutical Case Reports https://www.journalijmpcr.com/index.php/IJMPCR <p style="text-align: justify;"><strong>International Journal of Medical and Pharmaceutical Case Reports (IJMPCR) (ISSN: 2394-109X)</strong> aims to publish case reports in the areas of medical and pharmaceutical sciences.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.&nbsp;</p> SCIENCEDOMAIN international en-US International Journal of Medical and Pharmaceutical Case Reports 2394-109X Pulpectomy in a Primary Tooth with Gemination: A Case Report https://www.journalijmpcr.com/index.php/IJMPCR/article/view/30134 <p>Developmental anomalies may affect the number and morphodifferentiation of teeth. Development of two teeth from one tooth bud gives rise to gemination. Geminated teeth with caries may lead to pulpal pathologies for which extraction may be a preferred treatment. We report a case of geminated maxillary carious primary incisor treated with pulpectomy in a five year-old child.</p> Farheen Tafti Ashwin Jawdekar ##submission.copyrightStatement## 2021-08-28 2021-08-28 6 14 10.9734/ijmpcr/2021/v14i330134 Management of Compromised First Permanent Molar with Triple Antibiotic Paste in a 12-year-old Child: A Case Report https://www.journalijmpcr.com/index.php/IJMPCR/article/view/30135 <p>In teeth with pulpal and periapical infection, various group of microorganisms are present. Inhibition of the growth of these microorganisms and suppression of their antimicrobial activity play a crucial role in the success of the endodontic management. Triple antibiotic paste has been reported to have an excellent antimicrobial efficacy and it can be useful in management of teeth with severe infection. A 12-year-old female child reported with pain and swelling in relation with a lower left first permanent molar. Clinical examination of the tooth revealed deep occlusal caries and dentoalveolar abscess. Radiographically, the carious lesion was seen involving the pulp with periodontal ligament widening and inter-radicular bone loss was observed (endo-perio lesion). Considering the position of the tooth and its strategic importance, a conservative approach to salvage the tooth using Triple Antibiotic Paste (TAP) as a medicament was employed with complete radiographic healing by 12 weeks. Subsequent obturation using lateral condensation with gutta percha followed by composite restoration and preformed stainless steel crown was performed. This case report focuses on the endodontic management of perforated first permanent molar with compromised periodontal support and significant bone loss TAP as medicament and Mineral Trioxide Aggregate (MTA) as perforation repair material. Based on the results it can be concluded that Triple Anitibiotic Paste (TAP) can be effective in the disinfection and sterilization of the root canals and repair of complex lesions.</p> Sayali A. Deolikar Laresh Mistry Ashwin Jawdekar ##submission.copyrightStatement## 2021-09-02 2021-09-02 15 24 10.9734/ijmpcr/2021/v14i330135 A Case Report on Late-onset Friedrich's Ataxia and Response on Parkinsonism Treatment https://www.journalijmpcr.com/index.php/IJMPCR/article/view/30133 <p>Friedrich's ataxia is a progressive neurodegenerative disease that affects the posterior cord of the spinal tract. We present a case of an 83-year-old male with resting tremor and rigidity that had gradually worsened over the past few years. The patient has been diagnosed with Friedrich's ataxia. Unlike typical Friedrich ataxia, this patient does not have a shortened life expectancy. There is a small percentage of atypical patients demonstrate late-onset of disease, isolated spastic paraparesis without ataxia, and retained or exacerbated deep tendon reflex. Although there is no association between Parkinson's disease and Friedrich's ataxia; in our case, treatment of tremor and rigidity improves the patient's quality of life.&nbsp;</p> Uma Datta Gupta Tutul Chowdhury ##submission.copyrightStatement## 2021-08-14 2021-08-14 1 5 10.9734/ijmpcr/2021/v14i330133